While the "mark file as reviewed" button is always available in the toolbar, moving the mouse up there to click it after you're done reading down through the diffs breaks your visual flow. Enter the new button that appears at the bottom of every diff Reviewable would like you to review:
Clicking it will do exactly what it says on the tin and it's conveniently placed to boot. Also, if you're not reviewing the latest revision or you're working in "review each commit" mode, this button will automatically advance your diffs to the next appropriate revision. (And for the keyboard devotees, yes, there's a new command you can bind.)
Along with this new feature I also made some small changes to the toolbar counter semantics. The "to review" counter now only considers the current diffs. If you mark all those diffs as reviewed, it will turn grey and show the overall number of files still unreviewed at the latest revision. If that grey number is not zero then the revision label in the "changes" area next to it will go red instead to prompt you to switch diff bounds and make the file counter red again.
Hopefully these updates will make your reviews more efficient, but as always please let me know if something is broken or doesn't make sense.